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HIV REVERSE TRANSCRIPTASE
Descriptors Found:
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DeCS
Descriptor
English
:
HIV Reverse Transcriptase
Descriptor
Spanish
:
Transcriptasa Inversa del VIH
Descriptor
Portuguese
:
Transcriptase Reversa do HIV
Synonyms
English
:
Reverse Transcriptase, HIV
Reverse Transcriptase, Human Immunodeficiency Virus
Transcriptase, HIV Reverse
Tree Number:
D08.811.913.696.445.308.300.750.187
D12.776.964.775.375.545.875
D12.776.964.775.375.750.187
D12.776.964.775.562.764.875
D12.776.964.970.600.850.375.545.875
D12.776.964.970.600.850.375.750.187
Definition
English
:
A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa subunits that are derived from a common precursor protein. The heterodimer also includes an RNAse H activity (
RIBONUCLEASE H
, HUMAN IMMUNODEFICIENCY VIRUS) that plays an essential role the viral replication process.
History Note
English
:
2008
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52726
Unique Identifier:
D054303
Occurrence in VHL
:
Similar:
DeCS